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CJC-1295 / Ipamorelin

CJC-1295 no DAC + Ipamorelin, Modified GRF 1-29 + Ipamorelin

A compounded combination of a short-acting GHRH analog (CJC-1295 no DAC) and a growth-hormone secretagogue (ipamorelin) that some providers use to support the growth-hormone axis.

Baseline Labs Required Compounded Subcutaneous injection (typically nightly) Prescription Consultation Required
Provider approval and a live video consultation are required before treatment. Schedule now →

What Is It?

This combination pairs CJC-1295 without the drug affinity complex (DAC) — a short-acting analog of growth-hormone-releasing hormone — with ipamorelin, a selective ghrelin-receptor agonist. Together, they act on two complementary pathways to stimulate pulsatile release of the body's own growth hormone. This product is compounded in the United States and is not FDA-approved. Some providers use it as part of a broader plan intended to support body composition, sleep, and recovery in eligible adults, always under monitoring. It is not a substitute for FDA-approved growth-hormone therapy. Note: the long-acting CJC-1295 with DAC version is not offered by VidaVital Medical.

What May It Support?

  • Body composition support
  • Lean-mass preservation during medical weight management
  • Sleep quality (being evaluated)
  • Recovery (being evaluated)

Which Programs May Include It?

Where It Fits

CJC-1295 (no DAC) stimulates pituitary GHRH receptors while ipamorelin binds ghrelin (GHS-R1a) receptors; together, they may amplify pulsatile growth-hormone release without meaningfully raising cortisol or prolactin.

Beginner
Provider-directed use
Intermediate
Provider-directed use
Advanced
Provider-directed use

Do I Need Bloodwork?

Baseline Labs Required

Regular follow-up with periodic IGF-1 and metabolic labs at intervals determined by the provider.

Likely baseline panel may include: CBC, CMP, A1c, Lipid panel, IGF-1, TSH, Free T4, Pregnancy test when applicable

Important Safety Information

Common side effects may include:

  • Injection-site reactions
  • Flushing
  • Headache
  • Light-headedness
  • Vivid dreams
  • Increased appetite (from ipamorelin's ghrelin activity)
  • Water retention
Serious WarningsMay increase IGF-1; excess IGF-1 signaling has been associated with cancer risk
May contribute to fluid retention or joint discomfort
May affect glucose metabolism
Should not be combined with other growth-hormone secretagogues by default

Drug interactions: May interact with corticosteroids, thyroid hormone, insulin, and medications that affect glucose metabolism. Provider should review the complete medication list before prescribing.

Contraindications:

  • Active malignancy
  • Disruption of the hypothalamic-pituitary axis
  • Pregnancy or breastfeeding
  • Known hypersensitivity to either component
Pregnancy & BreastfeedingNot recommended during pregnancy, while trying to conceive, or while breastfeeding.
Cancer-Related ConsiderationsNot for patients with active malignancy. Any personal or family history of cancer should be disclosed to your provider before considering this therapy because it can raise IGF-1.

Regulatory Status

This combination is not FDA-approved. It is dispensed in the United States only as a compounded prescription.

Compounded MedicationCompounded medications are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality before marketing.

Frequently Asked Questions

Is this growth hormone?
No. This combination does not contain growth hormone. It signals the pituitary to release the body's own growth hormone in a pulsatile pattern.
Why not the long-acting version with DAC?
VidaVital Medical offers only the no-DAC form. The DAC (drug affinity complex) version produces a sustained rise in growth hormone that some providers consider non-physiologic; VidaVital's clinical direction is to favor the shorter, pulsatile signal.
Do I need bloodwork before starting?
Yes. Baseline labs including IGF-1 are required so your provider can assess suitability and monitor safely.
Can I stack this with another growth-hormone therapy?
Multiple overlapping growth-hormone secretagogues are not recommended by default. Any combination is determined by the treating provider based on labs and response.

Consultation

Treatment is not automatically provided. A licensed medical provider must review your history, symptoms, medications, laboratory results, and treatment goals before determining eligibility.

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Not sure where to start?

Answer a short set of questions about your goals and health history and see educational Beginner, Intermediate, and Advanced pathways your provider may discuss with you.

Not Medical Advice

The information provided on this website is for general educational purposes and is not medical advice, a diagnosis, or a prescription. Treatment recommendations are not final until a licensed medical provider completes a live consultation, reviews your medical history and medications, evaluates relevant laboratory results, and determines that treatment is medically appropriate.

Compounded Medication Disclosure

Certain treatments may be prepared by a compounding pharmacy pursuant to an individual prescription. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness, or quality before marketing.

Results

Your results identify subjects to discuss with a provider. They do not establish medical eligibility or guarantee that any medication will be prescribed.

Emergencies

This website is not intended for emergencies. Call 911 or seek immediate medical attention for urgent or severe symptoms.