What Is It?
TB-500 refers to a synthetic fragment of thymosin beta-4, a small protein present in nearly every cell of the body. In animal and laboratory research it has been evaluated for effects on cell migration, actin regulation, and tissue repair, though robust human clinical trial data remains limited. In the United States, TB-500 is dispensed as a compounded prescription and is not FDA-approved. Some providers use it as part of a broader recovery plan for tendon, ligament, and soft-tissue goals, always under provider direction. It should not be represented as a cure or as capable of regenerating specific tissue.
What May It Support?
- Soft-tissue recovery (being evaluated)
- Joint and tendon support (being evaluated)
- Adjunctive support in a broader recovery plan
Which Programs May Include It?
Where It Fits
Being evaluated for effects on actin dynamics, cell migration, and local tissue-repair signaling; the full human mechanism is not yet established.
Do I Need Bloodwork?
Follow-up interval and testing are determined by the treating provider based on the overall recovery plan.
Likely baseline panel may include: Provider-determined based on history and treatment goals
Important Safety Information
Common side effects may include:
- Injection-site reactions
- Occasional fatigue after dosing
- Mild headache
- Light-headedness
Not established for use during pregnancy or breastfeeding
Should not be used in place of an evaluation for a serious injury
Drug interactions: Interactions are not fully characterized. Disclose all prescription medications, over-the-counter products, and supplements to your provider before starting.
Contraindications:
- Active malignancy without provider clearance
- Pregnancy or breastfeeding
- Known hypersensitivity to TB-500 or any product component
Regulatory Status
TB-500 is not FDA-approved for any indication. When prescribed by a licensed medical provider, it is dispensed as a compounded prescription.
Frequently Asked Questions
How is TB-500 different from BPC-157?
Do I need bloodwork before starting?
Does TB-500 regenerate tissue?
Is TB-500 right for me?
Consultation
Treatment is not automatically provided. A licensed medical provider must review your history, symptoms, medications, laboratory results, and treatment goals before determining eligibility.